Multiple Myeloma
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MULTIPLE MYELOMA
Multiple Myeloma
A disease that starts silently in the bone marrow but can be controlled with early intervention
Multiple myeloma develops with the uncontrolled proliferation of plasma cells in the bone marrow.
is a type of blood cancer. Plasma cells normally make antibodies as part of the immune system.
produce healthy blood cells. But in multiple myeloma, these cells become abnormal and stop producing healthy blood cells.
disrupts. This affects the bones, kidneys, immune system and blood-making processes.
Thanks to modern treatment methods, multiple myeloma is now a long-term manageable disease.
has become.
Symptoms
Symptoms of multiple myeloma can develop slowly and can be confused with other diseases. The most common Symptoms include
Constant bone pain (especially in the back and ribs)
Anemia (weakness, pallor, rapid fatigue)
Frequent infections
High calcium level (nausea, constipation, confusion)
Renal failure (high creatinine)
Weight loss and loss of appetite
Remember: Symptoms can vary from person to person and some patients are detected by chance.
Diagnosis Process
- Blood tests:
Total protein, serum electrophoresis
Free light chain analysis
Detection of M-protein (monoclonal protein)
Calcium and creatinine levels
- Urine test: Evaluation of Bence Jones proteins
- Bone marrow biopsy: Determination of plasma cell ratio
- Imaging:
◦ Low-dose CT, MRI or PET-CT to investigate bone lesions
CRAB Criteria (Important in Multiple Myeloma Diagnosis)
The following four main findings are sought in the diagnosis of multiple myeloma:
- C: Hypercalcemia
- R: Impaired renal function (renal failure)
- A: Anemia
- B: Bone lesions
Treatment Methods
The treatment plan is individualized according to the patient's age, general condition and stage of the disease.
Drug Treatments
- Proteasome inhibitors (e.g. Bortezomib)
-Immunomodulatory agents (e.g. lenalidomide)
- Corticosteroids
-Monoclonal antibodies (e.g. Daratumumab)
Autologous Stem Cell Transplant
- In young and suitable patients, transplantation is performed with the patient's own stem cells after high-dose chemotherapy
- May provide long-term remission (regression)
Radiotherapy
- Can be applied in areas with local bone pain and fracture risk
Support Therapies
- Bone preservatives (zoledronic acid)
- Anti-infection treatments
- Nutrition and psychological support
Process Management Suitable for Health Tourism Process Management Suitable for Health Tourism
- - Reports and test results are evaluated remotely
- - Bone marrow biopsy, genetic tests and treatment planning are performed from diagnosis
- - Stem cell transplantation process is organized if necessary
- - Accommodation, transfer, escort and remote monitoring support for international patients
Multiple myeloma is now a manageable disease. The important thing is early diagnosis, correct treatment and uninterrupted follow-up.
You can contact us to create your own treatment plan, get a second opinion or learn about stem cell transplantation.